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KMID : 0378019920350030061
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New Medical Journal
1992 Volume.35 No. 3 p.61 ~ p.66
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The Change of Clinical Symptoms and Improvement of CLO Test After Treatment of Antibiotics and Collodial Bumuth in Patients with CLO test Positive
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Abstract
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To determine the clinical importance of Helicobacter pylori infection, its association gastritis and the response to drug therapy, patients with CLO positive antral gastritis (n=21) were studied..
Gastroscopy, biopsy and CLO test were performed in patients with dyspeptic symptoms. CLO test is rapid, easy, very sensitive and specific test for detection of Helicobacter pylon. After 2 weeks medication of colloidal bismuth. amoxicillin and tinidazole and 1 week
discontinuation of medication, gastroscopy, biopsy and CLO test at antrum were followed. Gastroscopically partial improvement of antral. gastritis was found in 7 patients. complete improvement was not found. CLO test was negative in 11 patients (52.3%) after treatment. There were 42.9% of partial improved rate in histologic findings, no complete healing. The loss of clinical symptoms was in 61.9% after 2 weeks treatment.
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